BackgroundThe neuroplasticity hypothesis of major depressive disorder proposes that a dysfunction of synaptic plasticity represents a basic pathomechanism of the disorder.Animal models of depression indicate enhanced plasticity in a ventral emotional network, comprising the amygdala.Here, we investigated fear extinction learning as a non-invasive p
Disulfiram has been used in the treatment of alcoholism and exhibits an anti-tumor effect.However, the intracellular mechanism of anti-tumor activity of Disulfiram remains unclear.In this study, we focused on the modulatory role of Disulfiram via oncogenic factor carbonic anhydrase CA12 and its associated transporter anion exchanger AE2 in lung can
Objective.Chlorhexidine gluconate (CHX) is an irrigant with a reasonable antibacterial ability and rather high permeability yet often fails to remove the BIOACTIVE QUERCETIN EMIQ smear layer.To solve this problem, CHX is upgraded through its complexion with chitosan (CS).Methods.Molar roots are split longitudinally by a rotary diamond saw.Chlorhexi
Transcription rates of the genes AtKu70, AtRAD51, AtRad1, involved in maintaining Arabidopsis thaliana genome stability, in relation to the modification of phenotypic characteristics in irradiated plants and their progeny after the action of acute and fractionated X-ray radiation were studied.Differences in the transcription rate were measured by d